Doxycycline (Doxycycline Hyclate)

Doxycycline is used for:

Treating a wide variety of infections caused by certain bacteria. It may also be used to prevent or slow the progression of anthrax after exposure. It may also be used for other conditions as determined by your doctor, which may not be listed in the professional package insert.

Doxycycline is a tetracycline antibiotic. It works by interfering with the production of proteins needed by the bacteria to grow. Slowing bacterial growth allows the body's defense mechanisms (eg, white blood cells) to destroy them.

Do NOT use Doxycycline if:

• you are allergic to any ingredient in Doxycycline or another tetracycline
• you are taking acitretin, oral contraceptives (birth control pills), or penicillins (eg, amoxicillin)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Doxycycline :

Some medical conditions may interact with Doxycycline. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have diarrhea, a stomach or intestinal infection, or the blood disease porphyria

Some MEDICINES MAY INTERACT with Doxycycline. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or penicillinsbecause they may decrease Doxycycline 's effectiveness
• Acitretin or isotretinoin because side effects, such as increased pressure inside the skull (resulting in severe headaches and vision problems) may occur
• Anticoagulants (eg, warfarin), methotrexate, or methoxyflurane because the actions and side effects of these medicines may be increased
• Oral contraceptives (birth control pills) because their effectiveness may be decreased by Doxycycline

This may not be a complete list of all interactions that may occur. Ask your health care provider if Doxycycline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Doxycycline :

Use Doxycycline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Doxycycline is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Doxycycline at home, a health care provider will teach you how to use it. Be sure you understand how to use Doxycycline. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Do not use Doxycycline if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
• Doxycycline works best if it is used at the same time each day.
• To clear up your infection completely, use Doxycycline for the full course of treatment. Keep using it even if you feel better in a few days.
• If your doctor directs you to switch to medicine that you take by mouth, be sure you understand how to take it.
• If you miss a dose of Doxycycline , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Doxycycline.

Important safety information:

• Be sure to use Doxycycline for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• Long-term or repeated use of Doxycycline may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
• Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
• Doxycycline may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doxycycline. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Hormonal birth control (eg, birth control pills) may not work as well while you are using Doxycycline. To prevent pregnancy, use an extra form of birth control (eg, condoms).
• Lab tests may be performed while you use Doxycycline. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Doxycycline should not be used in CHILDREN younger than 8 years old; permanent tooth discoloration (yellow-gray-brown) may occur.
• PREGNANCY and BREAST-FEEDING: Doxycycline has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doxycycline while you are pregnant. Doxycycline is found in breast milk. Do not breast-feed while taking Doxycycline.

Possible side effects of Doxycycline :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; difficulty swallowing; inflammation of the tongue; loss of appetite; nausea; purple patches under the skin; sensitivity to sunlight; skin inflammation in the anal and genital areas; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bulging soft spots in infants; headache and/or blurred vision; increased pressure in the head; pain, swelling, or redness at injection site; vaginal irritation or discharge; severe reaction to the sun.